4-Pyridinecarbonyl chloride, 2-chloro- (9CI)

4-Pyridinecarbonyl chloride, 2-chloro- (9CI) - Names and Identifiers

Name	2-chloropyridine-4-carbonyl chloride
Synonyms	BUTTPARK 4357-04 TIMTEC-BB SBB005463 2-CHLORO-ISONICOTINOYL CHLORIDE 2-chloropyridine-4-carbonyl chloride 2-Chloro-4-pyridinecarbonyl chloride 2-Chloropyridine-4-carbonyl chloride 2-CHLOROPYRIDINE-4-CARBONYL CHLORIDE 4-Pyridinecarbonyl chloride, 2-chloro- (9CI)
CAS	65287-34-5
EINECS	214-589-6
InChI	InChI=1/C6H3Cl2NO/c7-5-3-4(6(8)10)1-2-9-5/h1-3H

4-Pyridinecarbonyl chloride, 2-chloro- (9CI) - Physico-chemical Properties

Molecular Formula	C6H3Cl2NO
Molar Mass	176
Density	1.418 g/mL at 25 °C
Boling Point	144-148 °C/10 mmHg
Flash Point	>110℃
Vapor Presure	0.0228mmHg at 25°C
pKa	-1.84±0.10(Predicted)
Storage Condition	Inert atmosphere,2-8°C
Refractive Index	n20/D1.566

4-Pyridinecarbonyl chloride, 2-chloro- (9CI) - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R34 - Causes burns R29 - Contact with water liberates toxic gas R14 - Reacts violently with water R25 - Toxic if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S8 - Keep container dry. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S30 - Never add water to this product. S23 - Do not breathe vapour.
UN IDs	3265
WGK Germany	3
HS Code	29333990
Hazard Note	Corrosive/Store under nitrogen
Hazard Class	IRRITANT

4-Pyridinecarbonyl chloride, 2-chloro- (9CI) - Introduction

chloride is an organic compound with a chemical formula of C6H3Cl2NO and a molecular weight of 162.00. It is a colorless to pale yellow liquid with a pungent odor.

The main use of calcium chloride is as a reagent and intermediate in organic synthesis. It can be used to synthesize various pyridine and heterocyclic compounds, and is widely used in the fields of pharmacy, pesticide and pigment.

The method of preparing the chloride is generally by reacting 2-chloropyridine with anhydrous acid chloride. The reaction conditions may employ a solvent catalyst, such as carbon tetrachloride or methylene chloride, and be carried out at low temperatures.

When using calcium chloride, be aware that it is irritating and direct contact with skin and eyes should be avoided. During the operation, good ventilation measures should be taken, and protective gloves, goggles and protective clothing should be worn. In addition, it should be stored in a cool, dry, closed container, away from fire and oxidizing agents.

Please note that the above is for reference only and is not an exhaustive description. Always consult chemical safety data and operating manuals, and follow proper laboratory safety practices before using the chloride.

Last Update：2024-04-10 22:29:15